Israeli-Dutch Innovation Center

LSH: Regenerative Medicine H2020 open call for proposals

  • Industry Life sciences and health

ID: SC1-BHC-07-2019 Type of action: RIA Research and Innovation action Deadline Model: single-stage Opening: 26 July 2018 Deadline: 16 April 2019 17:00:00 Brussels time Work programme: Health, demographic change and wellbeing Work programme year: H2020-2018-2020 Call name: Better Health and care, economic growth and sustainable health systems Call ID: H2020-SC1-BHC-2018-2020

Topic Description

Specific Challenge:

Regenerative medicine offers hope for untreatable disease and the ageing population, improved quality of life and reduced medical costs. However, so far, regenerative medicine has not yet proved itself in the clinic beyond rare diseases or conditions of limited public health importance. With recent scientific discoveries opening up new approaches to regenerative medicine, the challenge is to use these to extend the regenerative approach to major diseases and conditions.

Scope:

Regenerative medicine replaces or regenerates human cells, tissue or organs, to restore or establish normal function. Projects should focus on innovative translational research to develop regenerative processes towards the ultimate clinical goal of addressing unmet clinical needs of large patient groups. Proposals should be based on new approaches such as genome editing or gene therapy, transdifferentiation or in vivo reprogramming, cell therapy and transplantation, 3D bioprinting, organoids or use of combined products (non-exhaustive list for illustrative purposes only). In all cases, proposals should explain in what way their approach is regenerative. Research on improved methods of tissue and organ transplantation is included on the condition that there is a clear regenerative step in the process. The project may focus on any step(s) on the innovation chain, from early testing and characterization of regenerative mechanisms to preclinical research, proof of concept or clinical trial. Sex and gender differences should be investigated, where relevant. Projects should include a section on the proposed therapy's exploitation potential, regulatory and commercialisation strategy and how it would be made available and delivered to patients.

The Commission considers that proposals requesting a contribution from the EU of between EUR 6 and 8 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.

Expected Impact:

  • Potential new regenerative therapies to address unmet clinical needs of large patient groups identified.
  • Europe's position in translational regenerative medicine strengthened.
  • New therapies for major human diseases and conditions, and new approaches for therapy taken further in the development pipeline.

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  • Israeli-Dutch Innovation Center
    Embassy of the Kingdom of the Netherlands in Israel

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